What is DPT

DPT is a combination vaccine of diphtheria, pertussis, and tetanus.
The above three vaccines are used in Japan and Thailand because vaccination timing is simultaneous and there is no problem with mixed inoculation.
Further explanation will be presented below

What is Diphtheria

Diphtheria is a disease of the upper respiratory tract infected by diphtheriae bacterium.


It can be infected from diphtheriae patients. Such as direct physical contact with droplets breathed out into the air and infected skin.


Incubation period is usually about 2 to 5 days. Main symptoms are a sore throat, couugh, muscle weakness and nausea.


It is reported that vaccination can reduce 95% of the risk of diphtheria. It is a triple combination vaccination. (diphtheria, pertussis, tetanus)

What is pertussis

People get the bacteria by inhaling it, that are present in droplets released when patient coughs.


Pertussis can cause rapid coughs followed by a high-pitched “whoop” sound, until the face gets red, and inhale with a loud “whooping” sound. There is a possibility of becoming cyanosis if the patient is under 6-month-old. Especially infants younger than a month old are likely to be apnea.

Pertussis Encephalopathy may cause cramping or disturbance of consciousness. In this case, brain damage may remain even if pertussis is cured.


Vaccination is the best way to prevent pertussis.

What is tetanus

It is a disease of the nervous system, caused by Clostridium tetani. Tetai toxin can cause muscle spasms and breathing difficulties. There is an 80 to 90% possibility of dying from suffocation. The bacteria usually enter through wounds, affect the nerve and brain which leads to tissue damage.


Early symptoms of tetanus are stiffness of the neck, jaw, and shoulders, and lose the sense of taste. Eventually, the toxin reaches to a nerve center, and causes muscle spasm.

Major sources of infection

Tetanus bacteria is not transmitted by animals and people, but it is hidden in the dirt at a probability of 50%. Not only are children endanger of being infected, adults may be infected as well. Normally, as long as the wound is thoroughly washed and disinfected, the bleeding site will heal and will not be infected. When physical strength is declining or when stress is accumulating, the function of white blood cells becomes dull, in which may not completely elimated the bacteria invading the body. This may eventually lead to infection of tentanus.


It is difficult to cure tetanus. It is possible to prevent by using DPT vaccine.